This error message means that some other software on your computer is using the DNS port (53).
It could be that you are using "Internet Connection Sharing", which "maps" DNS requests and uses the same port (53) as DNS servers.
See How do I use Simple DNS Plus with Internet Connection Sharing?
Proxy servers often include a DNS proxy/mapping function which can cause this.
See How do I use Simple DNS Plus with a proxy server?
Other software like network monitors could also by occupying port 53.
To find out what software is using the DNS port, at a command prompt, type NETSTAT -nabp UDP to also see which application is using each UDP port.